Members of the network and OSBREAC have participated in a major study published October 23 in Nature and Nature Genetics.
As part of the Oslo Breast Cancer Consortium (OSBREAC), surgeons, oncologist and scientists from OUS have participated in the analysis of genetic data from 275,000 women, of whom 146,000 had been diagnosed with breast cancer.
Seventy-two new genetic variants that contribute to the risk of developing breast cancer have been identified by a major international collaboration involving hundreds of researchers worldwide. Of these variants, reported on October 23rd in the journals Nature and Nature Genetics, 65 are common variants that predispose to breast cancer and a further seven predispose specifically to oestrogen-receptor negative breast cancer – the subset of cases that do not respond to hormonal therapies. The findings are the result of work by the OncoArray Consortium, a huge endeavour involving 550 researchers from around 300 different institutions in six continents of which OSBREAC is a part of. The study has been covered by media world-wide such as CNN.
Full press release can be downloaded as a Word file here: BCAC Press Release.